If you were to go by BS 5588-4,
It would be something like this:
With 3 doors fully open(floor on which fire is on+floor just below+exit door)and all other doors fully shut,an air velocity of 2m/s should be achieved across the door area.
Assuming 2.1mx1m doors,
required air flow= 3x(2.1x1m2)x 2m/s=12.6 m3/s
You must add a safety margin for leakage from ducts,doors on other floors,wind effect etc.I have used figures as high as 1.25.
When all doors are closed,a pressure differential of 50 pa must be achieved between the stairwell and the corridor.The force that needs to be exerted at the door handle should not exceed more 100N.