Of course. Doubling the pressure of a low pressure stage, say 50 psig x 2 = 100 psig, vs doubling the pressure of a higher pessure stage, say 200 psig x 2 = 400 psig would require maybe 400/100, or 4 times the strength in materials to be provided. As pressure ratio goes up, so does temperature as well and the gas passing through a first stage is already hot, generally making each sucessive stage a bit more inefficient, so a given amount of power does that much relatively less work for each higher stage to the point where decreasing the ratio makes sense.
If it ain't broke, don't fix it. If it's not safe ... make it that way.