If by 'frame' you mean the core of the transformer, you should find the core grounded to the tank. On many transformers this ground connection is made to be accessible by opening manholes at the top fo the transformer.
This is so that you may intentionally remove the intentional ground so you can use a megger to check for inadvertent ground paths, which, as mentioned above, can result in circulating currents which cause core heating and corresponding problems in the transformer.
Finding that you have these inadvertent paths is cause of the transformer to be removed from service for remediation. I have heard of people using welding machines or other high-current sources to attempt to 'burn' the inadvertent ground away, but seriously, the work needs to be done properly and usually involves some serious work, including draining and de-tanking.
old field guy