Are you talking A/B? If so, sequencers are just file to word function blocks. Its gets the same result as using an indirect address in a MOV block. We use them all the time for our servo programs which consists of 40 steps. Each step consists of a position, speed, dwell time and some output functions. When the servo reaches the programmed we drive the sequencers to output the next step's data (position, speed, etc..). We didn't have to use a sequencer but I guess you can see what is going on a little easier since the sequencer has more information displayed. Some people use them to control the machine outputs (I think sort of like the way an old music box works) but I would never do that.