Noise attenuators generally address noise after it has already been created. You would be well served to try to not make so much noise in the first place. Inlet and outlet connections and duct design will be the most important factors in preventing noise.
Mixing box will not help at all, it will hinder. Physics.
Next will be proper selection of fan size and speed to get the design airflow and pressure without adding dampers, baffles etc. to burn off excess.
Achieving such a low noise in a mechanical room will be a difficult challenge, and really requires design from the beginning to do. I doubt that it will be possible if you are just trying to add band-aids on top of whatever equipment and ducting is already there.