It doesn't sound quite right. Unless there is an error with the negative sign, this implies your pump is acting as a turbine!
It is possible the assumptions you have used in your model don't match reality. Is any part of the pipe flowing part full?
Can you give us a more detailed description of how you came to this conclusion? A description of the system would also help (static elevations, pipe lengths, operating philosophy etc).
Once we do a "quick and dirty" HGL I'm sure it will be crystal clear!
Cheers
Aussie Mike