Don't bet on stop signs to discourage speeding. You may well find that mid-block speeds increase as frustrated drivers try to make up lost time.
I wouldn't be surprised if rear-ends did go up, but then again, they are often lower on the KABCO scale than right-angle crashes. Will it be better, worse, or a wash? Hard to say.
Is this a high-speed road? (going by 85th% speed, not speed limit, which sounds like it may well be unrealisticly low). if so, I'd look for other solutions.
Is there a sight distance problem for traffic on the side road? Can it be improved by clearing brush or cutting back hillsides? Often that will improve things as much or more than all-way stop control, without the increased delays for mainroad traffic, and the associated noise and air pollution.
Good luck, and keep us posted.
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