321bvc,
which kind of field are you operating subsea or surface wellhead?
Using Meoh to prevent hydrate formatuion is also linked to temperature variation. Can you provide mor details?
we normally use Meoh to prevent Hydrate formation on our subsea installation. we inject Meoh downstrean and upstrean of the choke before starting a well after a S/D. we continue Meoh injection till the subsea Tree temperature reaches circa 68 oF = ~ 20oC. I think this is normal practice.
Also with 300 bar upstream of your choke, I'm afraid that it might be a wee bit tough to overcome this pressure with Meoh injection pump. think about it?