My replys to you are the below?
1) Are you designing a pressure vessel or performing a fatigue analysis?
2) if you are performing fatigue analysis then we only care usually about the nozzle/shell junction really.
3) you might wanna look at mosses handbook for the primary stress around shell openings. Its somewhat conservative.
4) i usually do FEM to linearize the stresses. It’s not a straight forward path to do it, trust me.
5) read studies about linearizing stresses.
6) understand thoroughly all the types of stresses in division 2 like primary secondary and peak as well as bending stresses.
7) hire a Proffessional at this moment to do this task because trust me not a single soul can help you right now without fully understanding the project.
8) good luck.
Detailing is a hobby,