There are a couple of things wrong with your question.
1. It has no specific information on what the building is.
2. There is no model or any information on what you have modeled in ETABS. (Garbage in Garbage Out)
3. This might be a better posting in the Computers and Structures section, however it will get answered here.
Are you stating that the mass that ETABS comes up with is 80% more than your hand calculation or that your hand calculation has 80% more mass? I think this is a problem with the model and not the program, I would go back and look at what you are using to define the mass rather it just be member weights and additional mass or if you are using the mass from specific load combinations.
Scott B.