From Autodesk...
Issue
When you start AutoCAD 2000 the following error displays: Cannot initialize ASI.
Solution
This error occurs because the Data Access components were not installed when AutoCAD 2000 was installed on your workstation.
To install the Data Access components:
On the AutoCAD 2000 CD, locate the file mdac_typ.exe in the Data folder.
Double-click on the file.
When prompted, select Complete Install for the Data Access components.
When the installation is complete, restart your workstation and start AutoCAD 2000.