Grant is correct. Bars in the direction where a pile cap is acting as a single span have the most concentrated stress near the end of the compression strut The 2009 CRSI Design Handbook specifies that all bars should be hooked or headed on pile caps with 2, 3, 4, 5 6 7, or 9 piles. For caps over 8, 10, 11, or 12 piles, only the bars in the short dimension need to be hooked or headed, and they should be on the bottom layer.
While not always mandatory, final design for most pile caps should be developed using strut and tie (primarily to satisfy shear requirements of ACI 318-11 15.5, which references Appendix A.) We are working on revisions to the CRSI Design Handbook to incorporate this change.