CMillanR,
Your top image is simple and very clear. The centrelines indicate that everything is symmetric.
Consider your tolerances. I do stuff like this all the time, where I call up the mount face as the primary datum, and the holes as the secondary datum feature. I apply a fairly sloppy profile tolerance all around. My assumption is that the holes must clear fasteners, and that the outline is not critical.
In alternate situation, the relationship between the holes and one or two edges is critical. My secondary datum feature probably would be the long edge, and my tertiary datum feature, the short edge. I would make the thing asymmetric as a poka yoke to assure that the datum features are used for location.
You have requirements. Meet them.
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JHG