This is a HVAC issue. There is too much negative pressure inside the plant subject plant area. Typically a negative pressure is developed purposely inside areas where you want the air to flow in rather than flow out of. For instance in rooms or areas with chemicals (such as laboratories) you do not want positive pressure in those spaces that will push the air and chemicals out of the cracks of doors to hallways, etc, that have people in adjacent offices. Therefore the hazardous areas are always maintained at negative pressure relative to other adjacent areas.
That being said the typical negative pressure is only on the order of 0.1 inches of water gauge. To develop a force of 100 pounds on a door of say 3 ft wide x 7 ft tall you would need a negative pressure inside the room of about 1 inches water gauge. If you really have 1 inches water gage negative pressure this is a poor design and I believe against building codes.
In order to create negative pressure your building must be exhausting more air than is being supplied by ventilation through supply fans or through ventilation air from HVAC units. The exhaust fans will keep sucking air out of a room based on their exhaust flowrate. If not enough makeup air is supplied through the supply fans or HVAC unit to balance the exhaust flowrate, the extra exhaust air comes through cracks in the doors and window. In fact this is how a system is designed to have flow from adjacent spaces into the hazardous space and not the other way around. The exhaust air fans are purposely designed to have more flow than the makeup air to the room from supply fans or ventilation air from HVAC unit so the difference must flow though cracks in doors. However the design difference between supply air and exhaust air is maintains such that the room will maintain a negative pressure of only about 0.1 inches wg not 1 inches wg.
In your case there is not enough cracks in the room to let enough air into the room to balance the flow of the exhaust fans unless the pressure is reduced in the room to a very low value (1 inches wg). Therefore you need to install a louver in the wall to allow more air into the room, or increase the ventilation air into the room from the HVAC unit or makeup air fans, but not too much so you still maintain a negative static pressure of about 0.1 inches wg but not 1 inches water gage.
You need someone to do an evaluation of your HVAC, ventilation and exhaust system air flows to determine the required fix. For a HVAC engineer this is a very minor task. You should not correct the problem by trying to make the door easier to open with some type of lever. If someone gets hurt opening the door your company can be sued as the internal pressure in the room is against Codes.