I've only had about 9 months of experience since graduating with my MS but I'd have to say that my firm is about 50-50 in regards to hand calcs and software. We use both Risa and RAM products to model structural systems, but tend to design typicals sections, simple beams and frames, slabs, retaining walls, etc. by hand. We've had good experience with the RAM software for steel design and are making use of it to automate beam design for some garages and concrete buildings we're currently working on.
We make extensive use of ENERCALC as a check of hand calcs and software output from the modeling software. Most of us use tons of MathCAD templates and Excel spreadsheets for repetative design processes, like torsion in concrete beams, snow loading, and anchor bolt connections, to name a few.
Also, whenever I personally run into something that is unique, like FRP reinforcement for example, I prefer MathCAD to spreadsheets because I can easily track the process of design and analysis. Most of my templates are crammed with notes and references to Code requirements and textbooks. Most of use tend to whip up a quick diagram or sketch to include in those templates to clarify input/output too.