Duwe6 ...ADD 250#!!!
jmilano ...Not sure if it is clear, but 150# & 300# are ASME ratings for forged steel flanges ...as Duwe6 pointed out. 125# & 250# are cast iron ratings.
According to pg. 162 of my Tube-Turn Catalog 411
..."detailed flange calculations are made following the Rules for Bolted Flanged Connections in Section VIII (Unfired Pressure Vessels Code) of the ASME Boiler Construction Code"