Eric,
I have been involved with bulk storage tanks for many years and have seen many tanks equipped with a "dip tube" for filling.
Yes, there will be some small escape of liquid from the vent hole during filling. But the benefit of the vent hole (also called the siphon breaker) outweighs any other minot buildup of charge that it may incur.
Most importantly, understand if you have a liquid with a high potential to build up a charge and ensure that you are using metallic pipe and that the piping and tank all have grounds that are in good shape. I have seen many plants where the tank/skid grounding cable is missing or has been eroded away.
In my opinion all tanks should have two functioning grounds
Eric, specifically what liquids are you dealing with ?
-MJC