How much flow in each fluid would be optimum?
How much delta T between the two fluids?
How much are you trying to "improve things" between what you are using now?
How much money do you want to spend?
How "important" is the heat exchange, and which fluid (hot fluid or cold fluid) is more important to optimize? (Are you trying to heat the cold fluid by a little bit, cool the hot one by a lot, or "get as much as possible" out of the hot fluid "as cheap as possible"?
Those are a lot of questions, let me see if I can make their answers more obvious by using a couple of examples. We don't know enough to give you real answers, and you obviously don't want to pay for a real shell-and-tube heat exchanger.
Drill two holes 1 inch dia in the Al block, run both in parallel.
Drill two holes 1 inch dia, run the two counter-flow.
Drill 4x 1/2 holes for the coolant, and 4x 1/2 holes for the hot fluid.
In a 12 x 12 x 12 AL block, drill 4x 1 inch dia hot fluid holes, and 32 1/2 dia coolant fluid holes around each hot fluid hole in a octogon. Run fluids parallel or counter-flow. (Headers are tricker.)
In a 12 x 12 x 12 Al block, run 5x 1 inch dia hot fluid holes through East-West, alternating levels with 5x coolant fluid holes 1 inch dia running North-South. Put the headers across the ends to collect the outlets and dispurse the inlets.