This sounds like a misapplication. I believe the Iris dampers try to maintain a fixed flow to maintain the stack velocity. The only trouble is that the demand from your hoods already determines what flow should be. The Iris dampers are creating a second flow criterion in series with the more important first. The result is a battle for control. For example if hoods demand 7,500 cfm and the Iris dampers control to maintain 10,000 cfm to keep the right stack velocity, the Iris dampers will be wide open when hoods are in a low flow condition. If hood use increases to a 12,000 cfm demand, the Iris damper will close down and only maintain 10,000 cfm. The result is low flow and improper control at the hoods.
Locking them in position as you mention is a good quick fix, and you're right - restricting the discharge will cause fan inlet pressure to become less negative, causing your VFD to increase speed.
-CB