dnmb, standard practice for testing is using a blower discharging through an orifice meter into a blanked-off portion of duct to measure leakage. The DP across the orifice correlates with a known flow, which is the leak rate from the duct.
To find every last microscopic leak humanly possible, we've injected sulfur hexafluoride (SF6) into a Powercat blower that discharges into the tested portion of duct. We scan the duct top-to-bottom, all surfaces, with an ITI/Qualitek Leakmeter 200 to find any leakage. Tin knocker follows us with a bucket of duct sealant (that gray gooey stuff) and seals until the Leakmeter smells no more SF6. Is this a standard? This is much better than the "standard" standard's I've seen from SMACNA, ASHRAE, etc... It's ridiculous to go to this level for normal applications. This is for Biosafety Level 3+ type installation.