Drweig,
The problem with having sensor at the end of long loop would be too much pressure at the coils closest to pumps, which cannot be overcome with coil balancing (even automatic balancing) valves. such scenario can take place in case of partial load, of course, which is always the worst case for balancing analysis.
Of course, measures must be taken to supply adequate dp to the most distant coil. if automatic balancing valves are used, that can be solved by applying minimum dp on the most distant coil (at design stage), so that balancing valve can slightly open when not having enough flow.
3/4 is arbitrary figure taken by analogy with vav systems. in most cases that should be verified during calculation stage if possible.
i strongly believe, and it is confirmed in practice almost every day, that vsd pumps and automatic balancing valves, while relieving lot of commissioning burden, put significantly more burden on design work, design have to be more precise and more elaborated, or new technologies will not only be waste of money, but they can even show worse results than traditional techniques.