Gungadinn:
You don’t compare them, except to note that mild stl. has a lower Fy & Fu than the high strength stl. And, you will quick discover that you want the lt.wt.(light weight/dead load) of the trailer to be a min. so as to maximize the trailer’s cap’y., and still stay within a gross weight. Then you wrestle with the thought that these trailers take a lot of abuse, and the owner/driver always thinks that they should carry half again as much as the advertised cap’y. So, you don’t want to design them too lightly; they have to be tough and you do have to pay close attention to deflection. I have actually seen the underside dragging on the ground in some instances, not so good. Also, you don’t want vibration, particularly harmonic vertical motion to make it act like a rubber band, going down the road. The steel you select should be weldable, of course, and it should be tough in terms of fatigue resistance. Be careful to use good clean details in you fabrication and welding, and at transitions us fairly generous curvature as the members change shape and slope. Pay some attention to the difference in the way a large tracked machine loads the trailer, vs. how a large rubber tired vehicle loads at four more concentrated points; or how a steel drummed roller applies a line load across the trailer. The main frame consists of a center sill and two side sills, with regular cross members to tie them all together across the trailer. Then, there are some fairly drastic changes in shape and configuration at front, to the fifth wheel; and at the back over the rear axles, tires and suspension. Lowboys are really an interesting structure and design problem.