You almost have your answer there in your 2nd post, 98769876. Unless you are also measuring flow rate, you can't compare the current pressure drop of the filter at the current (unknown) flow rate to the pressure drop of a new, clean filter at that (unknown) flow rate.
If you do know the flow rate, you can calculate what the pressure drop would be at the design flow rate and compare it to your standard for time-to-change-it pressure drop. But pressure drop across the filter is not linear. The pressure drop will rise in proportion to the square of the flow. At 2X flow rate, differential pressure will be 4X. At 1/2 flow rate, differential pressure will be 1/4. I'm assuming here that your liquid is incompressible and there is no flashing at the control valve.
If you don't know the flow rate, it really will be hard to do. I don't think you can assume that the flow rate even at wide-open valve will not vary, but if it is constant you can measure your pressure drop across the filter (new) at wide-open valve, then periodically during tank fills at wide-open valve. Or, if you know the valve's characteristics it might be possible to estimate flow rate by observing the differential pressure across the control valve. Best would be a reasonably-accurate flow measuring device.
As for position of filter relative to control valve, TD2K covered that nicely.
Good on ya,
Goober Dave
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