IRstuff,
Yes, I'm aware of your points. Still, the costs, slow orbiter redeployment, and accident history indicate that the shuttle concept may not have been the best solution for supporting orbital activities, given the state of technology in the early 1970s when it was selected over competing concepts.
By the way, I mentioned Soyuz and Apollo only in terms of Occam's razor (minimum as appropriate for the job), not as potential shuttle concepts. Nevertheless, reusable, upsized Apollo and Gemini variants were seriously considered, in combination with heavy lift rockets, as alternatives to a shuttle for orbital transportation.
Unfortunately for NASA, calling the shuttle re-useable has turned out to be quite a stretch, since post-flight refurbishment and launch costs are said to be several hundred million dollars each. You may remember that the shuttle vehicle was initially sold as a low cost launcher that could be rapidly turned around in two weeks at most and do each mission for a maximum of $30 million. Inflation accounts for some of the difference, but not a factor of 10 or so.
The shuttle was originally supposed to be much smaller, but in order to drum up support in Washington, NASA got the Air Force to agree to use the shuttle instead of their own planned launch platforms (upgraded missiles). It was the Air Force payload weight and size requirements that made the shuttle so large; and its single-orbit-launch-and-return-to-Vandenberg mission that required delta wings. In the end, the Air Force went back to its missiles for most of its launches anyway, leaving NASA with a behemoth it hadn't initially wanted.
So the shuttle, impressive as it is (and it most certainly is), is based on a design concept created by an unusual degree of political compromise and squeezed by budget compromises over a period of 12 years. It's a wonder that it has done so well. The delta-winged concept has operational advantages, though not used, but the tiles, booster rockets, and huge external fuel tank have been true Achilles’ heels. The report cited in the first post of this thread lists other issues, such as the lack of crew protection and escape capabilities, in Chapter 10.