"quark" is on the mark here! What "washford" is describing is a secondary loop using a refrigerant rather than a water/glycol solution. No, I dont believe he/she means a cascade system nor a sub-cooling loop.
I have done something similar, except I used LN2 as the primary cooling and R22 as the secondary loop. R22 was chosen because at low operating temperature there is little change in viscosity thus pump requirments were not heavly impacted. R22 remained in the liquid state all the time due to system pressure and temperature range. Also the customer had severe restrictions regarding spillage, residue, etc...
We can speculate why "washford" wants to use a refrigerant for his purpose, but what he/she is asking is real and possible.
"washford" if you can please supply more information so we all can chime in with good ideas and advice.
Good Luck
pennpoint