0l3675:
How is it that you have already selected a plate heat exchanger among other types? Obviously some engineering work has already been done, albeit preliminary. The choice is a good one; however, the selected exchanger is subject to proprietary design and is not an open science as is the design of shell & tube units.
TD2K's recommendation is right on target. That is the way these specific applications are carried out in the real world. Unless you've a resume full of successful plate exchanger designs and applications, you have no business trying to upstage the experts. Anyone outside of a proven and experienced manufacturer trying to design and fabricate a plate exchanger is either on an expensive and risky ego trip or is trying to work an academic homework assignment. I presume your application is neither of these exercises and that you will closely follow TD2K's advisement.