Hallec,
I am at a start-up firm here and I am setting up CAD standards. I have created title blocks for A[ ]size portrait, A[ ]size landscape, and B[ ]size landscape. I have no intention of going further. We don't have a full sized plotter, and our vendors and customers do not have them either. I have set the fonts to .08" (2mm), with .12" (3mm) titles. This is readable, and it makes efficient use of space on the drawing.
E[ ]size solves problems on a drafting board, not on a modern day CAD[ ]station.
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JHG