By not connected to a load, do you mean energized but no load? If so, the worst condition for a cable is to be energized but have no load (current) through it. The cable is subjected to voltage stresses without the benefit of heating from the load current. This will shorten the life.
If the cable has been sitting in conduit or tray, de-energized and you are thinking of energizing it, I would probably do some testing such as a megger.
Cables are affected by environmental factors (especially organic insulations) by water, radiation, sunlight, heat oxidation, etc. Also the operating environment where the cable is installed can affect the life - salt spray, chemicals, etc.
Hope that helped
wbd