Yes it is acceptable if I understand you correctly. I would not call i t a column tho, I would call it a hanger. Also when you have connections like that, pay close attention to the prying action of the hanger connection on both ends.
By the way, I have designed an entire mezzanine without any column because the client wanted a clear open floor free of columns. I had to suspend the entire mezzanine floor from the rood structure above.
Good luck.