Usually, this sort of joint is on door-skin outers to inners, or similar situations (the cosmetic outer is hemmed around the edge of the structural inner), so no spot-welding. Yes, you need to make sure the adhesive/sealant squeezes completely out both ends of the joint to avoid moisture trapping points. Beyond that, it's going to depend upon (a) how strong the joint needs to be, (b) how good (accurate/consistent) your stampings are, (c) what your hemming tooling is capable of. 6mm sounds about right, though I've seen more.