Sean -
We use tnxTower. It can be cumbersome to use at times, especially with towers that have complicated geometries. As msquared48 indicated, tnxTower does export to RISA-3D which is versatile and useful for special applications. I cannot speak for the other programs, but would be interested in what others think about them.
I am not sure if you have to do seismic design on each tower. As per ANSI-TIA-222-G-2 (Addendum 2):
2.7 Earthquake Loads
2.7.3 General
"Earthquake effects may be ignored for structures assigned to structure Class I in accordance with Table 2-1 or for any structure located in a region where the earthquake spectral response acceleration at short periods(Ss) from 2.7.5 is less than or equal to 1.00. Further, for structures without irregularities as described in Table 2-9, earthquake effects may be ignored when the total seismic shear is less than 50% of the total horizontal wind load without ice."
2.7.5 references Ss periods given in Annex B and Appendix 1 except as provided by 2.7.5.1.
Annex B references ASCE7-05
Here in the Midwest we rarely encounter a site that has a Ss greater than 1.00, save Southern Illinois/Missouri. However, I imagine if you are in area with high seismicity this would be a concern.
ANSI-TIA-222-H is supposed to come out in Spring 2016, however it seems that the revised TIA code would address topography, mounts, potential fatique, exposure and load factors.