Attached powerpoint is the results of using the previously-attached spreadsheet to try to model a wide range of shaft to shaft misalignment conditions. There are four variables: Shaft, Coupling, Bearing, Misalignment. Each of these variables is varied in two configurations: Shaft is thin or thick. Coupling is hard (stiff) or soft (flexible). Bearing is hard (stiff) or soft (flexible). Misalignment is offset or angle. This creates 16 possibilities which correspond to 16 slides in attachment.
In each slide we have one between-bearings shaft on left, one between-bearings shaft on right, and the shaft extensions and coupling between the inboard bearings of those machines (4 bearings total). In case it is difficult to see how x-coordinate of the graph relates to the machine: the four bearings are at the locations of the 4 dark-purple-colored spikes (dark purple is "force" and the spikes are the reaction forces at the bearings). You can also see that shear is integral of these discrete forces, moment is integral of shear, slope is integral of moment (with 1/EI factor), and displacement is integral of slope.
You can see from the results that the reaction force at the bearings depends on all those variables (stiffness of bearings, stifness of shaft, stiffness of coupling, nature of misalignment). Also will depend on the distances between bearings etc.
The geometric inputs should be easy to get (representative shaft sizes and distance between bearings). The stiffnesses will be the tricky part. As mentioned above coupling stiffnesses might be available from manufacturers. (I have seen some links discussing these values somewhere). As far as "bearing stiffness", it would actually represent series combination of bearing stiffness and support stiffness. Knowledge of this variable is also a prerequisite for rotordynamic analysis, and there is plenty of literature on how to estimate it. You could look for representative values in textooks. You could do a bump test with instrumented hammer and look at low-frequency asymptote to estimate stiffness. You could also push with a pressure-instrumented jack and measure movement with dial indicator. I doubt anyone here will be that energetic...
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(2B)+(2B)' ?