I believe what determines the classification of an area is the presence of flammable vapor, dust, etc. If a partition or fire wall can cause an area to no longer contain such vapor, etc., then I don't see why it would need to remain a classified location.
I'm thinking of automotive service shops that have a dividing wall between the service bay and the customer waiting area. The auto bay is classified, the waiting area is not.
Of course, as above, the point of origin of the vapor or dust would still remain classified, up to the limits set by the NEC.