The tube yield strength change is due to the fact that A500 Grade C is equally as common as A500 Grade B, to the point that pretty much every tube out there is "dual certified" to meet the requirements of both. A500 Grade C is now shown as the preferred material in table 2-4. A1085 comes at a premium, and at least in my part of the world is still not a regularly used grade.
There are a lot of very small changes to flexure and compression checks for non-compact and slender elements. Single angle bending has been modified in chapter F as well.
There also has been some moving around of the HSS failure modes from chapter K into chapter J.
Some dimensions, mainly the fillet stuff (K1, K, and T) for WF shapes have been changed a bit to match current rolling practices.
Haven't even gotten into the seismic manual yet, myself.