Short answer- differential protection on transformers will trip on transformer energization because the supply side CT's see the magnetizing inrush current and the load sides don't. Magnetizing inrush current has 2nd harmonics. Restraining or blocking on 2nd harmonics prevents false trips on energizing.
5th Harmonic currents occur when a transformer is overfluxed / over-excited. Additional magnetizing current goes in but doesn't come out. Again, blocking keeps the unit on-line, preventing a false trip.
Only reason to block on third harmonics is if the high harmonic content falsely actuates the differential protection. But then you have an expensive differential relay that is turned off most of the time by the load currents. You only want to block when an off-normal, non-destructive condition is momentarily present and could cause a false differential trip.