Any floor plate will naturally be broken up into rectangular/triangular sections (In your case, all rectangles), unless it's curved, which is a whole other problem (and even then, structurally, it's probably just triangles).
You don't need 1 area load for the whole floor, any sub-set of area loads that fill the whole area and land on members at each of their edges should be fine. Even weird shapes can be alight, but I try and help RISA out as I can when I'm modeling, I at least keep things nice and square where possible. I would probably draw your area loads between each girder line, and at each change in building perimeter, which likely corresponds to a girder line.
Modeling properly in RISA (or any FEM modler) is kind of an art, less an exact science.