Not totally unusual - but your turn is too sharp. It will slow down the flow and solids will come out of suspension.
Move the horizontal (part just upstream of cleanout) down the sheet, move the cleanout out to the left of the pipe.
Also, do not show the horizontal sanitary under the exterior wall. This will likely have structural implications since these walls tend to support buildings. Depending on how the structural is designed, you might not be able to bring your drains back into the wall. If you can, I would recommend bringing the drains from your lavatories into the vent pipe of the water closet (known as a vertical wet vent).