We always were forced by old spacecraft company spec's. to use lockwire for all fasteners. Nylon patch type threadlockers were not suitable due to high launch vibration (i.e. they didn't hold), Locktite adhesives were banned due to outgassing, and thread-deformation types were banned due to lack of re-usability, and fear that burrs raised in assembly could come adrift in space and cause all sorts of problems. YMMV, what does the vehicle spec./design standard call out?