db80,
If this is your first attempt at rectangular flanges there are somethings to consider when designing rectangular chamber flanges that are to be used with rectangular covers.
Box flange distortion due to welding in the long sides of the rectangles can be considerable. It sometimes pays to leave a larger "Edge Distance" at bolt holes to accomadate bowing due to the bar-to-side-wall welds.
If your fitters and welders are also unfamilar with this configuration, a lot of time and expense may be required to straighten edges.
If configuration allows, bolt rectangular flange bars to cover before welding-out. If you don't intend to bolt together, Do NOT Drill until Header is completed.
Stiffeners between the inner box walls help, but residual stress may still bow in sides when these are removed.
Depending on materials of construction, and client requirements, it sometimes pays to leave extra material in flange width and mill off after welding, thus matching dimensions of the cover and preserving edge distance.
If you are in a fabrication shop, get some feed back from your floor people before you specify your materials to purchasing.
"Round things are better"