@Pavel_1976, the DEP states those are acting simultaneously in the notes. For other Clients as well that is understood to be acting simultaneously and you can change it to the resultant value for nozzles on spheres or ellipsoidal heads.
API 660~663 as well provide nozzle loading tables, but those are sometimes overridden by the Client/Contractor specification.
Those tables were established before UG-44(b) was introduced and some nozzles would automatically have to increase flange rating just to pass with those table values for local stress and UG-44(b) on the flange.