If you pump liquid in a closed loop, and you attach a reservoir that communicates with the atmosphere, that reservoir becomes sort of a reference point. If it's attached to the pump suction, the entire loop will run at a positive pressure. If it's attached to the pump discharge, the entire loop will run at a negative pressure.
... after everything stabilizes.
... roughly.
... absent other influences.
Mike Halloran
Pembroke Pines, FL, USA