We use MasterCAM here, (manufacturing gas turbine components) and we love it. It's very easy to use, (I basically taught myself to use it), and we now use it for all our 3D modelling.
Its one of these 'tick the box' type CAM packages, where you choose the area you want to machine, and then choose from a huge series of options to machine the part the way you want. You can also get third party plugins (C-hooks) to give you extra functionalitly, or write your own.
It works fine with Acad, though the converter is an additional extra. We havn't lost any data in the conversion yet.
It has a rather basic verification program, which isn't a patch on something like Vericut, but it is quite handy and fast. Customer support is great...we've run into a few minor bugs, (doing what we do, we tend to push CAM programs to the wall) and they've been dealt with quickly. They are also open to suggestions for the program to be improved.
We looked at about 25 CAM packages for our work, and this is the one we chose.