About a year ago We had to deal with 240 deformed thread locknuts. Non-stainless hardware, and Despite using a MIL spec graphite-in-alcohol lube, galling to some degree was common and prevailing torque was all over the map, between modest to nearly the max for the fastener. As the nuts' function was strictly to set a dimension it was OK.
If instead bolt clamping was important we would have had a tussle keeping track of all the prevailing torques at initial installation, and retorque would have been a small nightmare.
The disadvantage of all types of locknuts is they may try to trick me into thinking they (the locknuts) are sufficient, and proper torque is not THE pre-requisite for a successful dynamically loaded structural joint. Some days I doubt or forget that friction from bolt applied clamping is critically important. All I have to do to get back on the right track is look at the pictures of the damaged crankshaft key I took out of our Integra after a few hundred miles of gentle street running. As a secret favor to me and my spare time my wife and daughter had a recommended local mechanic (also a motorcycle "racer") change the timing belt and water pump on my daughter's car. Afterwards It was way down on power, despite him insisting he "re-checked" it 3 times. At that point In tears my daughter told me her car was messed up. On my way in to check the cams' timing (one cam was a tooth off, which also made the cam mounted ditributor out of range on ignition timing) the crank bolt was obviously under-torqued at maybe 20 lb-ft. The crank key's faces already had visible steps pounded an easily detected few thousandths deep. tick, tick, tick, BOOM.
In 86 cases out of 100 a locknut buys a few extra hours of service (which can be quite useful) while the poor bolt dies a painful death acting as a pin, but not having the nut "loosen" in the first place would be way better.