Due to the combined tolerances in the mating parts of a spline connection (lead/profile deviations, index errors, runout, etc), it is impractical for even very accurate splines to ensure uniform load distribution with an interference fit. Even a small amount of angular shaft displacement will create large stress concentrations in the spline contacts. Thus it is generally best to design the spline connections with some small amount of clearance to permit sliding.
With regards to fretting of the spline contacts due to relative motion, it is basically impossible to prevent this from occurring, even with an interference fit at the spline flanks. So you must either design the spline to accommodate the fretting (as is typically done), or you must use some other form of shaft connection that will not experience any relative motion at the connected interface (like bolted flanges, curvics, shrink fits, etc).