I agree with JLSeagull, even if I never could have an experimental confirmation of this feeling (and, of course, I would be curious to see, ehm... to hear about some kind of correlation between any acoustic measure and actual leak rate).
In more general terms, EN 1779 standard (Edition 1999 + Amendment 1 dated 2003) about Non-destructive testing - Leak testing - Criteria for method and technique selection may be helpful when choosing how to detect a gas leakage based on the type and shape of the object under test and on the entity of the leakage itself; moreover, the typical accuracy ranges for each method (e.g. tracer gas, vacuum, pressure change, bubbles, etc...) are also given and the influence of pressure, temperature and nature of gas on leakage is also studied.
Unluckily, this standard excludes hydrostatic, ultrasonic or electromagnetic methods (for which other reference documents must be applied).
See also thread408-150132 within this Forum...
Coming back to reysor's question, I would also suggest the pressure change method: of course this is feasible if there is another valve tight enough (or if it is possible to blind the pipe off) downstream the instrument valve under examination...
In any case, I believe that it should be the plant on the field to dictate the allowable leak rate and not just a standard on the paper. In other terms: why taking the valve off the line if you can't even notice the leakage? ;-)
Hope this helps, 'NGL