Jigneshpadia2002
Bioengineer
- Jun 4, 2005
- 69
Hi there,
I am working on a small scale spinner system for growing mammalian cells. Spinners are labscale instruments which are very different in terms of geometry of the impeller comapre to large scale or pilot scale bioreactors. Problem with this spinners is that there is no scale-up information available from the vendor or in literature. Spinners have impeller driven by magnetic force while bioreactors will have impeller driven by motor. Another complication is that the spinners have entirely different type of impeller, which raises question about the effective impeller diameter. I know that dimensional analysis solves this kind of complicated issues very easily but I don't know how to start for this problem.
Any help?
Thanks a lotin advance.
I am working on a small scale spinner system for growing mammalian cells. Spinners are labscale instruments which are very different in terms of geometry of the impeller comapre to large scale or pilot scale bioreactors. Problem with this spinners is that there is no scale-up information available from the vendor or in literature. Spinners have impeller driven by magnetic force while bioreactors will have impeller driven by motor. Another complication is that the spinners have entirely different type of impeller, which raises question about the effective impeller diameter. I know that dimensional analysis solves this kind of complicated issues very easily but I don't know how to start for this problem.
Any help?
Thanks a lotin advance.