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Hi, We are constructing a new pharmarceutical facility now. I was ask to come up a master validation plan. Can someone give me some guildance or example plan? What items should I check for buildings, utilities and HVAC system? Many thanks

We are designing a purified water system with one stage RO. One article about RO system said the pH of the water inlet to RO has to be adjusted to above 8.3. The reason is there will be only HCO3- and CO32- ions in the water, and not CO2 gas since RO can not reject CO2 gas. Does anyone use RO...

Hi, all, Do you have any idea that the minimum temperature of the water outlet that a cooling tower(natural draft/mechanical draft) can reach? Thanks

Hi, all, We plan to build a hot oil boiler to heat all the reactors in our plant. Due to the different temperature requirement of individual reactor, someone in our company brough up the following design: 1. Feed a medium(say kind of oil) in the reactor jacket 2. Install a sort of...

Hi, all, My boss said that somebody told him that if a water ring vacuum pump was installed in a high position(say, on the roof of the plant), then you can get better vacuum. Did anyone hear about this? Is there any theory or logic behind this? Thanks

Dear all, I have one project to get a better control for a vessel during heating/cooling. There are steam and water line for this vessel. Currently,steam is on for a few minites to reach to certain temperature. Then open water vavel and crack steam valve to maintain the target temperature. My...

Hi, all, Can anyone explain the sentence below? Inductive load: 50VA @120VAC OR 240VAC What if the voltage is 220VAC? THANKS

Dear all, I have a solenoid valve with 220V/50Hz. Can I use a controller with on-off control relay to operate this solenoid valve? Thank you

Dear all, Can anyone tell me what is the meaning of (class F coil with 18" lead)? Is there any other class of coil? What is their major difference? Thanks a lot

Hi, all, I am wondering whether a vacuum pump can be used to assist condensate flow back to a condensate receiver. Normally, there is a vent in the receiver to vent the flashed steam generated by high pressure condensate. How can I handle the flashed steam problem if a vacuum is used? What kind...

Hi, all, Does anyone have some ideas about the M2 controller? How does it work? What's the adventage? What is the difference between this controller and the other controller? Thanks

If there are two reactors heated up by steam. The steam header pressure is same, say 6 bar. But the two reactors need different steam pressure due to the different process(say reactor 1 needs 5bar which reactor 2 needs 1bar). Therefore, the inlet steam pressure is regulated by cracking the...

We have water ring vacuum pump. When we pull vacuum from reactor, organic fumes will come out of the reactor and enter into the vacuum pump water line, which cause contamination issues in my waste water system. We tried to keep the water into a circulation tank without any cooling, but the water...