Seeking Guidance on Developing an Adhesive Coating Formula

Whatever it is that barnacles produce would be a top contender.

Example: https://news.mit.edu/2021/barnacle-glue-wound-seal-0809

Thank you for sharing this! It's truly fascinating but still in the research phase from what I see. Do you know of any similar commercially available adhesives?

Something derived from barnacles couldn't be used on Muslims or devote Jews.

Perhaps you could explore synthetic chewing gum formulations, FDA approved surfactants and/or moisture scavenging surface treatment. Maybe consider a two-step process. Localized primer and application, followed by the coating/membrane. Polyisobutylene appears to be the main component, it is insoluble and indigestible. It might be worth considering that the coating/membrane could be heated, to a comfortably acceptable temperature, if conformability is a requirement. There are a number of medical grade chewing gum patents established for drug delivery. A top shelf Polyisobutylene producer likely has starter formulas. Whether something is chewy or pliable is a matter of composition.

My dental hygienist puts fluoride varnish on my teeth at the end of my tooth cleaning ordeals. The stuff sticks to my teeth and stays there for several hours, or until I eat or drink or brush my teeth.

According to:


...the varnish is shellac or urethane based, and formulated to dry quickly and adhere in the presence of saliva. There are tons of variations on the market, so some research into those might be appropriate.

Other dental adhesives that work well are based on acrylate chemistries (super glue) that cure in the presence of moisture, these work well for temporary crowns. There are lots of others out there, and google will point you to dozens; most of these are not going to be very flexible, as they are intended for permanent boding of crowns/caps and other dental hardware, directly to prepared tooth surfaces.