After reading up again I think you just use Antoine's to get the vapor pressure of both, then use Rault's to get the partial pressure and thus, the mole fraction.
Need some help extracting this from my brain. I need to calculate the vapor composition of 60%isopropanol/water mixture at atmospheric pressure and 160 F (for scrubber emissions estimate). Tried running a flash in aspen but nothing flashes. I feel like this should be easy to calculate by hand...