×
INTELLIGENT WORK FORUMS
FOR ENGINEERING PROFESSIONALS

Log In

Come Join Us!

Are you an
Engineering professional?
Join Eng-Tips Forums!
  • Talk With Other Members
  • Be Notified Of Responses
    To Your Posts
  • Keyword Search
  • One-Click Access To Your
    Favorite Forums
  • Automated Signatures
    On Your Posts
  • Best Of All, It's Free!
  • Students Click Here

*Eng-Tips's functionality depends on members receiving e-mail. By joining you are opting in to receive e-mail.

Posting Guidelines

Promoting, selling, recruiting, coursework and thesis posting is forbidden.

Students Click Here

Jobs

solubility parameters

solubility parameters

solubility parameters

(OP)
how can I calculate Hansen solubility parameters of liquid pharmaceutical excipients for oral drug delivery?
is it possible to determine saturation amount of liquid excipient in typical solvent as ethanol or acetone?
thanks

RE: solubility parameters

Dear Tp51

There are various options for doing this.

1. Use group contribution approach available online (eg: http://www.capsolva.dk/propertypredict.asp)

2. More advanced "plotting" approches based on whatever solubility data you have available.

For calculating direct solubility one can use Scatchard/Hildebrand theory -- but it will be a rough estimate. Personally I have had more luck in applying local thermodynamic models - however these require some form of experimental data.

Let me know if this is still something you are working on -- I'll be happy to try to guide you in the right direction.

Best regards

Peter

Red Flag This Post

Please let us know here why this post is inappropriate. Reasons such as off-topic, duplicates, flames, illegal, vulgar, or students posting their homework.

Red Flag Submitted

Thank you for helping keep Eng-Tips Forums free from inappropriate posts.
The Eng-Tips staff will check this out and take appropriate action.

Reply To This Thread

Posting in the Eng-Tips forums is a member-only feature.

Click Here to join Eng-Tips and talk with other members!


Resources